Effect of Temperature
At first it would seem that the Arrhenius equation 5.24 would be all that is needed to describe the temperature effect. In fact, it does hold, but only in the lower range of temperatures associated with life. At higher temperatures another reaction occurs the dena-turation of the enzyme. One way to handle this is to treat the denaturation reaction as a simultaneous equilibrium. The dissociation equilibrium constant, Kd, is related to temperature by where AGd, AHd, and ASd are Gibbs free energy,...